Refills is a cash-pay GLP-1 telehealth platform built around one idea that sets it apart from most of the market: the price does not change when your dose does. Compounded semaglutide is advertised at $99 per month and compounded tirzepatide from $159 per month, at every dose. In a category where escalating to a maintenance dose routinely doubles your bill, flat pricing is a structural difference worth understanding. This review evaluates Refills across pricing, medications, eligibility, fulfilment, support, and competitive positioning.

Quick Takeaway:

• Cash-pay telehealth platform advertising compounded semaglutide at $99/month and tirzepatide from $159/month
• Flat pricing: the advertised rate applies at every dose, with no escalation penalty
• Marketed as personalised GLP-1 injections from around $5 per day
• Onboarding is a short online quiz followed by licensed provider review, with free shipping
• No insurance; compounded medication is not FDA-approved

Looking for a Better Alternative?

While Refills offers genuinely aggressive flat pricing, CoreAge Rx is our top-rated favorite for GLP-1 weight loss therapy. CoreAge Rx combines competitive pricing with exceptional customer service, faster medication delivery, and more comprehensive support resources.

Why we recommend CoreAge Rx:

• Lower monthly costs than most competitors ($179–$399 range)
• Faster prescription approval (typically 12–24 hours)
• More extensive provider support included at no extra charge
• Better medication availability during shortages
• Higher patient satisfaction scores (4.7/5)

Refills competes hard on headline price. CoreAge Rx competes on what is included at that price — provider messaging, titration management, and support that does not thin out once you are subscribed.

New Patient Special: Save up to $200 on your first three months. Same-day prescription approval for qualifying patients. Rated 4.7/5 stars by verified customers. No insurance required.

Overview: What Is Refills?

Refills is a direct-to-consumer weight care platform connecting patients with licensed providers who prescribe compounded GLP-1 medication, dispensed through partner pharmacies and shipped to the patient. Its marketing leads with affordability and simplicity — a three-minute quiz, provider review, free shipping, and no membership fee layered on top.

Its distinguishing commercial claim is dose-flat pricing. Most compounded providers tier by dose, so a patient who titrates from 2.5 mg to 10 mg tirzepatide sees their monthly cost rise substantially. Refills advertises the same price at every dose, which changes the economics for anyone expecting to reach a high maintenance dose.

Medications Offered and Compounded Status

Refills offers compounded semaglutide and compounded tirzepatide as once-weekly injections through its weight care programme.

Important: These are compounded preparations, not FDA-approved finished medicines. Compounded drugs are not reviewed by the FDA for safety, effectiveness, or quality before they are marketed. That is the trade-off behind the price. Our compounded versus brand-name guide explains what this means in practice, and it is worth reading before you choose on price alone.

Ask Refills directly which pharmacy dispenses your prescription and whether it is a 503A pharmacy or an FDA-registered 503B outsourcing facility — the oversight differs meaningfully between the two.

Consultation Process and Provider Involvement

1. Take the quiz. Refills advertises a roughly three-minute online intake covering health history, weight, and goals.
2. Provider review. A licensed clinician reviews your submission and determines whether GLP-1 therapy is appropriate.
3. Plan selection. Choose semaglutide or tirzepatide; billing cadence affects the effective rate.
4. Fulfilment. Medication is dispensed by a partner pharmacy and shipped, with free shipping advertised.
5. Ongoing care. Refills and provider contact for dose questions and continuation.

Review is asynchronous in the usual pattern for this segment — you are unlikely to speak to a clinician by video unless you request or require it. That keeps costs down and puts the burden of accurate disclosure on you. Our consultation guide covers what to prepare.

Eligibility and Lab Requirements

Refills applies standard anti-obesity medication criteria: generally a BMI of 30 or above, or 27 or above with at least one weight-related condition such as type 2 diabetes, hypertension, dyslipidaemia, or obstructive sleep apnoea.

Routine laboratory testing is not typically required before an initial prescription at platforms in this segment. If you have any history of thyroid disease, pancreatitis, gallbladder problems, or diabetes, obtain baseline labs independently and share them. Contraindications are the class standard: personal or family history of medullary thyroid carcinoma, MEN2 syndrome, pregnancy, breastfeeding, and known hypersensitivity. See our eligibility guide.

Pricing

Pro Tip: Flat pricing is worth most to patients who expect to titrate high. If you settle at a low dose, a tiered provider may cost less; if you reach a tirzepatide maintenance dose, flat pricing can save several hundred dollars a month against dose-tiered channels. Model your likely maintenance dose before comparing. Our flat-rate versus dose-tiered pricing guide works through the arithmetic.

Check Refills Pricing

Compounded semaglutide advertised at $99/month and tirzepatide from $159/month, at the same price for every dose, with free shipping and licensed provider review.

Pharmacy Fulfilment and Shipping

Prescriptions are dispensed through partner compounding pharmacies and shipped directly, with free shipping advertised. Injectables require cold-chain handling: refrigerate on arrival, inspect the solution before every dose, and observe the beyond-use date, which is shorter for compounded preparations than for manufacturer product. See our storage and shipping guide.

Support Services

Support is lean and access-focused:

• Provider messaging for dose and side-effect questions
• Continuation and refill management
• Educational content on injection technique and expectations

There is no coaching curriculum, dietitian relationship, or structured behavioural programme. Refills sells affordable medication access and prices accordingly.

Cancellation, Refunds, Insurance, and HSA/FSA

Cash-pay platforms in this segment generally allow cancellation through the account portal, which stops future shipments rather than refunding medication already dispensed — prescription preparations cannot be returned to stock. Multi-month billing plans that lower the effective rate are correspondingly harder to unwind. Confirm the current cancellation and refund terms in writing before you subscribe, since these vary and change.

Refills does not bill insurance. Medically supervised weight management is generally an eligible HSA and FSA expense; keep itemised receipts and confirm substantiation requirements with your plan administrator. Our insurance, HSA and FSA guide covers this.

Pros and Cons

Pros

• Among the lowest advertised compounded GLP-1 pricing in the market
• Flat pricing across doses removes the escalation penalty
• Free shipping included
• Simple, fast onboarding
• Both semaglutide and tirzepatide available

Cons

• Compounded medication is not FDA-approved
• No insurance billing or prior authorisation support
• No coaching, nutrition, or behavioural programme
• No routine lab requirement before prescribing
• Largely asynchronous care with limited clinical depth

Who It May Be Best For, and Limitations

Best for: Cost-focused, self-directed patients who understand GLP-1 therapy, expect to titrate to a higher dose, and want the lowest predictable monthly outlay.

Limitations: Patients new to GLP-1 therapy who need clinical hand-holding, patients with insurance coverage worth pursuing, patients wanting FDA-approved branded medication, and anyone needing structured behavioural support.

Alternatives to Refills

Frequently Asked Questions

How much does Refills cost per month?

Refills advertises compounded semaglutide at $99 per month and compounded tirzepatide from $159 per month, with the same price applying at every dose. It also frames pricing as from around $5 per day. Confirm current pricing and billing cadence at checkout.

Does the price go up as my dose increases?

Refills advertises the same price at every dose, which is the platform's main commercial differentiator. Most compounded providers tier pricing by dose, so this matters most for patients expecting to reach a high maintenance dose.

Does Refills prescribe brand-name Wegovy or Zepbound?

Refills' advertised offering is compounded semaglutide and compounded tirzepatide. Compounded preparations are not FDA-approved products. If you specifically want branded medication, manufacturer channels such as LillyDirect and NovoCare® Pharmacy are the relevant comparison.

Does Refills take insurance?

No. It operates on a cash-pay basis. Costs may be reimbursable through an HSA or FSA with itemised receipts.

Is shipping included?

Refills advertises free shipping with its weight loss plans.

Are compounded GLP-1 medications safe?

Compounded drugs are not FDA-approved and are not reviewed by the FDA for safety, effectiveness, or quality before marketing. Quality depends on the dispensing pharmacy. Ask which pharmacy fills your prescription and whether it is an FDA-registered 503B outsourcing facility.

Bottom Line

Refills is competing on price, and by advertised numbers it is competing successfully — $99 semaglutide and $159 tirzepatide at any dose sits at the low end of the entire US market.

Strengths: very low advertised pricing, flat dose structure, free shipping, simple onboarding, both medications available.

Drawbacks: compounded rather than FDA-approved product, no insurance handling, no behavioural support, and no routine laboratory baseline.

Best for: informed, cost-focused patients expecting to titrate high.

Skip if: you want branded medication, insurance advocacy, or clinical hand-holding.

Flat pricing is a real advantage, but price is only one variable. Confirm which pharmacy dispenses your medication, get baseline labs yourself if the platform does not order them, and know how quickly you can reach a clinician when side effects hit during titration.

CoreAge Rx: one all-in monthly price from $179–$399 including medication, unlimited provider messaging, and titration support, with 12–24 hour approvals. Save up to $200 on your first three months.

Medical disclaimer: This article is for informational purposes only and is not medical advice. GLP-1 receptor agonists are prescription medicines with real risks and contraindications. Compounded medications are not FDA-approved products. Always consult a qualified healthcare professional before starting, changing, or stopping treatment. Pricing changes frequently and should be verified directly with the provider.

Sources: Refills published weight loss programme and pricing pages; FDA guidance on human drug compounding; FDA prescribing information.

Date reviewed: August 2026